You can obtain advice on Therapeutic Drug Monitoring (TDM) from your ward pharmacist (via pager) or by contacting the Queensland Children’s Hospital (QCH) Pharmacy Department.

Paediatric TDM differs from that relating to adults, so please don’t hesitate to contact your Clinical pharmacist for advice regarding starting doses, or advice on interpreting blood levels and advice regarding appropriate dose adjustments.

Gentamicin and Tobramycin

• Paediatric Tobramycin/Gentamicin Therapeutic drug monitoring form (QH staff only)
• AUC Calculation tool for Tobramycin and Gentamicin (QH staff only)
• Medication safety communique – Changes to Tobramycin immunoassay and results reporting (QH staff only)

Note: Interpretation of the plasma drug levels require knowledge of patient’s condition, weight, height, serum creatinine, drug dose, exact time of commencement and end of infusion (including mode of administration) and exact times of blood collections.

Please contact the AMS Pharmacist for more information on training and support for clinicians who would like to utilise the AUC calculation tool.

Amikacin – Seek ID specialist/pharmacist advice on monitoring and appropriate target levels.

• Vancomycin – therapeutic drug monitoring form
• Teicoplanin – seek specialist ID/pharmacist advice on monitoring and appropriate target levels.

• Itraconazole, Voriconazole, Posaconazole, Flucytosine
• Seek ID specialist/pharmacist advice on monitoring and appropriate target levels.

• Ganciclovir and Valganciclovir – seek ID specialist/ pharmacist advice on monitoring and interpretation of levels.

• Pathology test list